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4HF-09
- Development stage
- Preclinical
- Lead developer
- 4HF Biotec
- Modality
- Prodrugs/Conditional Activator Small Molecules → Small Molecules
01
Overview
4HF-09 is an early-stage small molecule drug conjugate (SMDC) being developed by 4HF Biotec for the treatment of stomach cancer. The drug is designed using 4HF Biotec's proprietary AI and data mining platform, which identifies specific cancer targets to enable the delivery of cytotoxic payloads directly to tumor cells via a small molecule ligand. This SMDC approach aims to enhance therapeutic efficacy while minimizing systemic toxicity compared to traditional chemotherapy. As of early 2024, the candidate is in the discovery phase, specifically undergoing in silico chemistry and medicinal chemistry optimization.
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