Drug intelligence / Profile preview

4R-Fluoro-N6-ethanimidoyl-L-lysine

Development stage
Unknown
Lead developer
Pfizer
Modality
Small Molecules
01

Overview

4R-Fluoro-N6-ethanimidoyl-L-lysine is a synthetic small molecule analog of L-lysine, specifically designed as a selective inhibitor of inducible nitric oxide synthase (iNOS). The compound features a fluorinated modification at the 4-position and an ethanimidoyl group at the N6 position. It has been studied for its potential to selectively inhibit iNOS activity, which may be relevant in conditions where excessive nitric oxide production contributes to pathology. The compound is considered experimental and has not been approved for any clinical indications[1][5][10].

Other names
(2S,4R)-2-amino-6-(ethanimidoylamino)-4-fluorohexanoic acid4R-fluoro-L-NIL
02

Targets

NOS2 (Nitric Oxide Synthase 2)

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