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**5-androstenedione** is a steroidal prohormone that serves as a precursor to testosterone in the body. It is structurally similar to 4-androstenedione but differs by the position of a carbon-carbon double bond. Once ingested, it can be converted into testosterone and other sex hormones such as estrone and estradiol. Its primary use has been as an oral supplement intended to boost testosterone levels for purposes like enhancing athletic performance, increasing muscle mass, energy, red blood cell health, recovery from exercise, and sexual function. However, scientific evidence supporting these effects is limited or inconclusive. Due to its anabolic properties and potential for misuse in sports doping, it is classified as a controlled substance in the United States and banned by major sporting organizations including the World Anti-Doping Agency[1][2][3][8].
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