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Drug intelligence / Profile preview
5-chloro-6-methyl-N-(2-phenylethyl)-2-pyridin-2-ylpyrimidin-4-amine
- Development stage
- Unknown
- Modality
- Small Molecules
01
Overview
A synthetic small molecule featuring a pyridine and pyrimidine core structure, substituted with chloro, methyl, and phenylethyl groups. It is classified as a pyrimidylpyridine derivative. The compound has been referenced in chemical databases but does not have an established pharmaceutical use or approved indication. It is known to interact with methionine aminopeptidase enzymes (MAP1 and MAP2), suggesting potential activity as an inhibitor of these targets[1][2]. Methionine aminopeptidases are involved in the removal of N-terminal methionine residues from nascent proteins—a process relevant to cell growth and proliferation.
- Other names
- 5-chloro-6-methyl-N-(2-phenylethyl)-2-pyridin-2-ylpyrimidin-4-amine5-chloro-6-methyl-N-(2-phenyethyl)-2-pyridinylpyrimidinamin5-chloro-6-methyl-N-(2-phenyethyl)-2-(pyridinyl)pyrimidinamin4-pyrimidinamine, 5-chloro–6-methyl–N–(2–phenylethyl)–2–(pyridin–2–yl)–
02
Targets
METAP1 (Methionine aminopeptidase 1)METAP2 (Methionine aminopeptidase 2)
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