5-fluoroindole propanol phosphate

5-Fluoroindole propanol phosphate is a synthetic small molecule belonging to the class of 3‑alkylindoles, characterized by an indole core substituted with a fluorine atom and a propanol phosphate side chain. It is primarily used as an experimental biochemical tool and not as an approved pharmaceutical agent. The compound acts as an inhibitor at the alpha site of tryptophan synthase, interfering with the enzyme's function in tryptophan biosynthesis. Its structure allows it to bind specifically to the alpha subunit of tryptophan synthase, stabilizing certain conformational states and providing insight into allosteric regulation mechanisms within this enzyme complex[8][9]. There are no known clinical indications or therapeutic uses for this compound; its main application is in structural biology and enzymology research.

Other names

3-(5-fluoro-1H-indol-3-yl)propyl dihydrogen phosphate(3-(5-fluoro-1H-indol-3-yl)propoxy)phosphonic acid[3-(5-fluoro-1H-indol-3-yl)propoxy]phosphonic acid