Drug intelligence / Profile preview

5-imino-4-(3-trifluoromethyl-phenylazo)-5H-pyrazol-3-ylamine

Development stage
Preclinical
Modality
Small Molecules
01

Overview

**Mechanism of Action:** This compound is a small molecule inhibitor of methionine aminopeptidase (MAP), an enzyme involved in the removal of N-terminal methionine from nascent proteins. Inhibition of MAP can affect protein maturation and function[6][8]. The drug is currently experimental and has not been approved for any therapeutic indication. **Additional Information:** The compound is a solid belonging to the benzene and substituted derivatives class. It has been studied primarily as a research tool for understanding methionine aminopeptidase function in bacteria such as Escherichia coli[6][8].

Other names
4-(2-(3-(trifluoromethyl)phenyl)hydrazin-1-ylidene)-4,5-dihydro-3H-pyrazole-3,5-diimine4-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}-4,5-dihydro-3H-pyrazole-3,5-diimineSCHEMBL23752416SCHEMBL-23752416SCHEMBL 23752416SCHEMBL23752417SCHEMBL-23752417SCHEMBL 23752417BDBM17853BDBM-17853BDBM 17853DB08666DB-08666DB 08666
02

Targets

METAP2 (Methionine aminopeptidase 2)

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