Drug intelligence / Profile preview

5-Loxin BSO

Development stage: Unknown
Lead developer: Laila Impex
Modality: Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration: Oral

Overview

5-Loxin BSO is a proprietary botanical extract derived from *Boswellia serrata*, developed by Laila Impex. It is an enhanced formulation of 5-Loxin, which is standardized to contain 30% 3-O-acetyl-11-keto-beta-boswellic acid (AKBA). The 'BSO' designation likely refers to the inclusion of Boswellia serrata oil or a specific oil-based delivery system intended to improve the bioavailability or efficacy of the active boswellic acids. The drug acts as a selective inhibitor of the 5-lipoxygenase (5-LOX) enzyme, thereby reducing the production of pro-inflammatory leukotrienes. It is primarily investigated for the symptomatic treatment of osteoarthritis, particularly of the knee, where it has demonstrated efficacy in reducing pain and improving physical function in clinical trials.

Brand names: 5-Loxin BSO
Other names: Boswellia serrata extract BSO

Targets

ALOX5 (Arachidonate 5-lipoxygenase)

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