Drug intelligence / Profile preview

5-MeO-DMT

Development stage
Phase 2
Lead developer
Eli Lilly
Modality
Small Molecules
Administration
Inhalation, Intranasal
01

Overview

5-MeO-DMT (5-methoxy-N,N-dimethyltryptamine) is a potent, fast-acting psychedelic tryptamine that acts as a non-selective serotonin receptor agonist, with particularly high affinity for the 5-HT1A and 5-HT2A subtypes. Benuvia operates as a contract development and manufacturing organization (CDMO) that produces high-purity, synthetic, GMP-grade 5-MeO-DMT for use by pharmaceutical and biotech clients in clinical research. The compound is currently being investigated for its therapeutic potential in treating psychiatric conditions such as treatment-resistant depression, anxiety, and post-traumatic stress disorder (PTSD). Unlike longer-acting psychedelics like psilocybin, 5-MeO-DMT is characterized by a rapid onset and short duration of action, often lasting less than 30 minutes.

Other names
5-methoxy-N,N-dimethyltryptamineN,N-Dimethyl-5-Methoxy-Tryptamine
02

Targets

HTR2A (Serotonin receptor 5-HT2A)SERT (Sodium-dependent serotonin transporter)HTR1A (Serotonin receptor 1A (5-hydroxytryptamine receptor 1A))

Beyond the preview

Go deeper on 5-MeO-DMT.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on 5-MeO-DMT.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call