5-phenylsulfanyl-2,4-quinazolinediamine

A synthetic small molecule with the chemical formula C14H12N4S and a molecular weight of approximately 268.34 g/mol. It is an experimental compound that has been studied primarily as an inhibitor of dihydrofolate reductase (DHFR), a key enzyme in folate metabolism essential for de novo glycine and purine synthesis and DNA precursor synthesis. The drug has not been approved for any indication and is not known to be in active clinical development or marketed anywhere[1][2][6]. Its primary mechanism involves targeting DHFR; however, it may also interact with other related enzymes based on protein binding data[1][6].

Other names

5-(phenylsulfanyl)quinazoline-2,4-diamine5-PHENYLSULFANYLQUINAZOLINE-2,4-DIAMINE5-PHENYLSULFANYL-2,4-QUINAZOLINEDIAMINE5-(Phenylsulfanyl)-2,4-chinazolindiamin5-(Phénylsulfanyl)-2,4-quinazolinediamine5-thiophenylquinazoline diamine