6-hydroxynorleucine

6-Hydroxynorleucine is a synthetic amino acid derivative classified as an l-alpha-amino acid. It features a hydroxyl group at the sixth carbon of the norleucine backbone. This compound is primarily used in research and drug development as a building block for peptide synthesis and protein engineering, enabling the creation of novel peptides with enhanced stability or biological activity. It has been investigated for potential pharmaceutical applications in treating infectious diseases such as malaria and sepsis, as well as neurodegenerative conditions like Alzheimer's disease and Parkinson's disease. However, it is not currently approved for clinical use in any indication[1][2][4][5].

Other names

L-6-hydroxynorleucineL6-hydroxynorleucineL 6-hydroxynorleucineepsilon-hydroxynorleucine(S)-2-amino-6-hydroxyhexanoic acidalpha-amino-epsilon-hydroxycaproic acidNorleucine, 6-hydroxy-DL-Norleucine, 6-hydroxy-L-Norleucine, 6-hydroxy-DL-Hydroxynorleucineracemic 6-hydroxynorleucineracemic6-hydroxynorleucineracemic-6-hydroxynorleucineHACA cpd