6-nitroindazole

6-Nitroindazole is a synthetic small molecule belonging to the indazoles class, characterized by a nitro group at the sixth position of the indazole ring. It is primarily used as an experimental tool in pharmacological and biochemical research. Its main mechanism of action is as an inhibitor of neuronal nitric oxide synthase (nNOS), thereby modulating nitric oxide (NO) production in biological systems. This property has made it valuable for studying NO-mediated signaling pathways, neurodegenerative diseases, and potential therapeutic interventions for conditions such as chronic pain, inflammation, depression, and anxiety. Additionally, it exhibits anti-inflammatory and neuroprotective effects in preclinical models[1][5][7].

Other names

6-nitroindazole6-nitro-1H-indazole6-nitro-2H-indazole1H-indazole, 6-nitro-6-nitroisoindazoleCCRIS 3263CCRIS3263CCRIS-3263EINECS 231-500-9EINECS231-500-9EINECS-231-500-9BRN 0007812BRN0007812BRN-0007812