Drug intelligence / Profile preview

64Cu-cunotadipep

Development stage: Preclinical
Modality: Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Peptides
Administration: Intravenous

Overview

64Cu-cunotadipep is an investigational **PSMA-targeted copper-64 radiopharmaceutical** developed as a positron emission tomography imaging agent for prostate cancer. It consists of a prostate-specific membrane antigen binding small-molecule peptide conjugated to the **NOTA** chelator and labeled with **copper-64**, enabling tumor localization by PET through selective accumulation in PSMA-expressing prostate cancer lesions. Based on the cited publication context, it was studied alongside the related DOTA-based analog 64Cu-cudotadipep to compare how chelator choice affects pharmacokinetics, suggesting a theranostic-oriented imaging platform rather than an approved commercial product.

Other names: copper-64 cunotadipepcopper64 cunotadipepcopper 64 cunotadipep64Cu-NOTA-PSMA

Targets

PSMA (Prostate-specific membrane antigen)

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