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Drug intelligence / Profile preview
64Cu-NOTA-PEG2Nle-CycMSHhex
- Development stage
- Preclinical
- Lead developer
- University of Colorado Denver
- Modality
- Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Beta-minus Emitters → Radiopharmaceuticals, Positron Emitters → Radiopharmaceuticals
01
Overview
64Cu-NOTA-PEG2Nle-CycMSHhex: sourced facts only. name: "64Cu-NOTA-PEG2Nle-CycMSHhex and 64Cu-NOTA-AocNle-CycMSHhex were readily prepared with more than 90% radiolabeling yields and showed MC1R-specific binding on B16/F10 cells." [PMID:35486894]; target: "64Cu-NOTA-PEG2Nle-CycMSHhex and 64Cu-NOTA-AocNle-CycMSHhex were readily prepared with more than 90% radiolabeling yields and showed MC1R-specific binding on B16/F10 cells." [PMID:35486894]; developer: "Department of Radiology, University of Colorado Denver, Aurora, Colorado 80045, United States." [PMID:35486894]; modality: "The B16/F10 melanoma lesions could be clearly visualized by positron emission tomography (PET) using 64Cu-NOTA-PEG2Nle-CycMSHhex as an imaging probe at 2 h post-injection." [PMID:35486894]; stage: "The B16/F10 melanoma lesions could be clearly visualized by positron emission tomography (PET) using 64Cu-NOTA-PEG2Nle-CycMSHhex as an imaging probe at 2 h post-injection." [PMID:35486894]
02
Targets
MC1R (Melanocortin Type 1 Receptor)
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