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68Ga-BRP-020063
- Development stage
- Unknown
- Lead developer
- BoomRay Pharmaceuticals
- Modality
- Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Peptides
- Administration
- Intravenous
01
Overview
68Ga-BRP-020063 is a Gallium-68 labeled radiopharmaceutical designed for positron emission tomography (PET) imaging of Nectin-4 expression in solid tumors. Developed by The First Affiliated Hospital of Soochow University, it specifically targets Nectin-4 (Poliovirus receptor-related protein 4), a cell surface protein frequently overexpressed in various cancers, including bladder, breast, and lung cancers. As a diagnostic tracer, it is used to evaluate the biodistribution, pharmacokinetics, and imaging characteristics of Nectin-4 positive lesions, potentially aiding in patient selection for Nectin-4 targeted therapies like enfortumab vedotin.
- Other names
- [68Ga]Ga-BRP-02006368Ga-labeled Nectin-4-targeted tracer
02
Targets
PVRL4 (Nectin cell adhesion molecule 4)
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