Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
68Ga-DOTA-A20FMDV2
- Development stage
- Preclinical
- Lead developer
- Queen Mary University of London
- Modality
- Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Positron Emitters → Radiopharmaceuticals, Peptides
- Administration
- Intravenous
01
Overview
68Ga-DOTA-A20FMDV2 is a radiolabeled peptide-based positron emission tomography (PET) diagnostic imaging agent targeting the integrin alpha-V beta-6 (αvβ6). The targeting moiety, A20FMDV2, is a 20-mer peptide derived from the VP1 coat protein of the foot-and-mouth disease virus (FMDV) that exhibits high selectivity and nanomolar affinity for αvβ6. The peptide is conjugated to the chelator 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) and radiolabeled with gallium-68 (68Ga). Developed by researchers at Queen Mary University of London, 68Ga-DOTA-A20FMDV2 is being investigated for the molecular imaging and staging of αvβ6-expressing malignancies, such as pancreatic ductal adenocarcinoma and breast cancer, as well as for evaluating the biodistribution and renal clearance of αvβ6-targeted radiopharmaceuticals.
- Other names
- [68Ga]-DOTA-A20FMDV2[68Ga]Ga-DOTA-A20FMDV268Ga-DOTA-A20
02
Targets
αVβ6 (Integrin αVβ6)
Beyond the preview
Go deeper on 68Ga-DOTA-A20FMDV2.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on 68Ga-DOTA-A20FMDV2.