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68Ga-DOTA-Bombesin
- Development stage
- Phase 3
- Lead developer
- Bayer
- Modality
- Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Peptides
- Administration
- Intravenous
01
Overview
68Ga-DOTA-Bombesin is a radiopharmaceutical imaging agent designed for use in positron emission tomography (PET)/magnetic resonance imaging (MRI) for patients with prostate cancer. This radioactive substance functions by attaching to specific receptors, primarily the Gastrin-Releasing Peptide Receptor (GRPR), which are frequently overexpressed on the surface of tumor cells. The binding of 68Ga-DOTA-Bombesin to these receptors allows for the visualization of cancerous tissue during PET/MRI scans, thereby assisting in the differentiation between tumor and healthy prostate tissue and potentially enabling the identification of smaller tumors than standard imaging methods.
- Brand names
- LNTH-2401LNTH2401LNTH 2401
- Other names
- Gallium-68 (68Ga)-DOTA-Bombesin
02
Targets
GRPR (Gastrin-releasing peptide receptor)
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