Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
68Ga-DOTA-ECL1i
- Development stage
- Unknown
- Lead developer
- Azienda Ospedaliero‑Universitaria di Parma
- Modality
- Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Positron Emitters → Radiopharmaceuticals, Peptides
- Administration
- Intravenous
01
Overview
68Ga-DOTA-ECL1i is a gallium-68 radiolabeled peptide-based positron emission tomography (PET) imaging tracer. It consists of the extracellular loop 1 inverso (ECL1i) peptide, a 7-D-amino acid allosteric antagonist of C-C chemokine receptor type 2 (CCR2), conjugated to the chelator DOTA and radiolabeled with gallium-68. The tracer is designed to non-invasively detect and track the recruitment of CCR2-expressing inflammatory monocytes and macrophages in vivo. It is primarily being investigated for molecular imaging in myelofibrosis, myocardial infarction, and other inflammatory or fibrotic conditions.
- Other names
- 68Ga-DOTA-ECL1[68Ga]68Ga-DOTA-ECL1i[68Ga]Ga-DOTA-ECL1igallium Ga 68 DOTA-ECL1igallium-68-DOTA-ECL1igallium68-DOTA-ECL1igallium 68-DOTA-ECL1i
02
Targets
CCR2 (Chemokine (C-C motif) Receptor 2)
Beyond the preview
Go deeper on 68Ga-DOTA-ECL1i.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on 68Ga-DOTA-ECL1i.