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68Ga-FAP-VG-02

Development stage: Preclinical
Lead developer: VitsGen Therapeutics
Modality: Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Peptides
Administration: Intravenous

Overview

68Ga-FAP-VG-02 is a Gallium-68 labeled diagnostic radiopharmaceutical developed by VitsGen Therapeutics. It is designed as a radionuclide drug conjugate (RDC) that targets fibroblast activation protein (FAP), an enzyme highly expressed on the surface of cancer-associated fibroblasts (CAFs) within the tumor microenvironment of various solid tumors. By binding to FAP, the Gallium-68 isotope allows for high-sensitivity positron emission tomography (PET) imaging, enabling the visualization and localization of FAP-expressing tumors. This diagnostic tool is intended to assist in cancer staging, patient selection for FAP-targeted therapies, and monitoring treatment response. The agent is currently in the preclinical stage of development.

Other names: 68Ga-FAP-VG-02Gallium-68 FAP-VG-02Gallium68 FAP-VG-02Gallium 68 FAP-VG-02

Targets

FAP (Fibroblast activation protein alpha)

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