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68Ga-G23
- Development stage
- Phase 2
- Lead developer
- The First Hospital of Fujian Medical University
- Modality
- Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Peptides
- Administration
- Intravenous
01
Overview
68Ga-G23 is a radiopharmaceutical PET imaging tracer developed by the First Affiliated Hospital of Fujian Medical University for the detection and staging of prostate cancer. It targets the Gastrin-Releasing Peptide Receptor (GRPR), a G protein-coupled receptor that is significantly overexpressed in various stages of prostate cancer, including primary tumors and metastases. As a molecular probe, 68Ga-G23 serves as a complementary diagnostic tool to PSMA-targeted PET imaging, particularly in patients with low or negative PSMA expression. It is currently being evaluated in clinical trials to determine its biodistribution, safety, and diagnostic efficacy in identifying biochemical recurrence and guiding treatment decisions.
- Other names
- Gallium-68 G23Gallium68 G23Gallium 68 G23[68Ga]Ga-G23
02
Targets
GRPR (Gastrin-releasing peptide receptor)
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