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68Ga-HSA
- Development stage
- Unknown
- Lead developer
- Peking University Cancer Hospital & Institute
- Modality
- Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
- Administration
- Intravenous
01
Overview
68Ga-HSA (Gallium-68 Human Serum Albumin) is a diagnostic radiopharmaceutical developed for positron emission tomography (PET) imaging. It consists of human serum albumin (HSA) labeled with the positron-emitting radioisotope gallium-68, typically using a chelating agent such as DTPA. Developed by the Peking University Cancer Hospital & Institute, the probe is primarily intended for the diagnosis and localization of protein-losing enteropathy (PLE), a condition characterized by the abnormal loss of serum proteins into the gastrointestinal lumen. Compared to the traditional SPECT tracer 99mTc-HSA, 68Ga-HSA offers superior image resolution, sensitivity, and signal-to-noise ratio, facilitating the identification of specific leakage sites in patients with hypoproteinemia or digestive system tumors.
- Other names
- gallium Ga 68 human serum albumin68Ga-labeled human serum albumin
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