68Ga-MI-0202C1

68Ga-MI-0202C1 is a gallium-68 (^68Ga)-labeled fluorinated benzamide derivative developed as a radiopharmaceutical tracer for **positron emission tomography (PET) imaging** of malignant melanoma. It targets **melanin** within tumor cells, enabling visualization of melanoma lesions, particularly in metastases. Preclinical studies demonstrated high radiochemical yield and purity, selective uptake in melanin-expressing cells, and low background uptake in non-target tissues such as lung, brain, and bone—organ­s commonly involved in melanoma metastasis. The structure incorporates a DOTA chelator, which influences its hydrophilicity and biodistribution. 68Ga-MI-0202C1 is primarily investigational and has shown promise for sensitive and specific detection of melanoma in animal studies[1].