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68Ga-NTA-476

Development stage: Phase 1
Lead developer: 3B Pharmaceuticals
Modality: Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics
Administration: Intravenous

Overview

68Ga-NTA-476 is a diagnostic radiopharmaceutical designed for positron emission tomography (PET) imaging of prostate cancer. It is a radionuclide drug conjugate that targets the prostate-specific membrane antigen (PSMA), which is highly expressed in prostate cancer cells. By binding to PSMA, 68Ga-NTA-476 enables sensitive and specific imaging of PSMA-positive lesions, aiding in the detection and management of prostate cancer. The agent uses gallium-68 as its radioactive component for PET imaging. The drug was initially developed by 3B Pharmaceuticals GmbH and has been evaluated in early phase clinical trials for its ability to visualize prostate tumors compared to standard-of-care agents.

Other names: [68Ga]Ga-NTA-476

Targets

PSMA (Prostate-specific membrane antigen)

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