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68Ga-R8760
- Development stage
- Discontinued
- Lead developer
- Radionetics Oncology
- Modality
- Small Molecules, Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics
- Administration
- Intravenous
01
Overview
68Ga-R8760 is a first-in-class, gallium-68-labeled small molecule radioligand imaging agent developed for the detection of adrenocortical carcinoma (ACC). It functions as a diagnostic radiopharmaceutical by selectively binding with high affinity to the melanocortin 2 receptor (MC2R), also known as the adrenocorticotropic hormone receptor, which is highly expressed on ACC cells. The agent enables PET imaging to localize and identify MC2R-expressing tumors, supporting patient selection for potential MC2R-directed therapies. Developed by Radionetics Oncology, this compound represents an innovative approach in precision oncology diagnostics for rare adrenal cancers[1][6][7].
- Other names
- gallium Ga 68 R8760
02
Targets
MC2R (Adrenocorticotropic Hormone Receptor)
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