7-Aza-L-tryptophan

**7-Aza-L-Tryptophan** is a synthetic analog of the amino acid tryptophan in which a nitrogen atom replaces the carbon at position seven of the indole ring, forming a pyrrolo[2,3-b]pyridine structure. It belongs to the class of L-alpha-amino acids and is primarily used as an experimental probe in protein chemistry and biophysical studies. The chromophoric moiety, 7‑azaindole, exhibits red-shifted absorption and emission compared to natural tryptophan and has unique fluorescence properties that are sensitive to its environment. This makes it valuable for studying protein structure and dynamics using optical methods. It can be incorporated into synthetic peptides or expressed proteins for research purposes but has no approved pharmaceutical or dietary supplement use.[1][6]

Other names

L-7-AzatryptophanL7-AzatryptophanL 7-Azatryptophan49758-35-272B59WRT3H(S)-2-Amino-3-(1H-pyrrolo[2,3-b]pyridin-3yl)propanoic acid