Drug intelligence / Profile preview

7-ketodehydroepiandrosterone

Development stage
Phase 2
Lead developer
Humanetics
Modality
Small Molecules
Administration
Oral
01

Overview

**Description:** 7-ketodehydroepiandrosterone (commonly known as "7-keto-DHEA" or "7-Keto") is a naturally occurring metabolite of the steroid hormone dehydroepiandrosterone (DHEA). Unlike DHEA, it is not converted to sex hormones such as androgens or estrogens in the body. It has been marketed primarily as a dietary supplement for weight loss and metabolic support. The proposed mechanism involves increasing thermogenesis by activating thermogenic enzymes, thereby potentially raising resting metabolic rate and promoting fat utilization for energy. However, clinical evidence supporting these claims remains limited and inconclusive; most studies are small or short-term[1][2][5]. The compound is generally well-tolerated but long-term safety data are lacking. It is not approved by the FDA as a pharmaceutical drug[5].

Brand names
7-Keto
Other names
7-ketodehydroepiandrosterone7-keto DHEA3-acetyl–7–oxo–dehydroepiandrosterone3-acetyl–7–oxo DHEA
02

Targets

HSD11B1 (11-beta-hydroxysteroid dehydrogenase type 1)

Beyond the preview

Go deeper on 7-ketodehydroepiandrosterone.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on 7-ketodehydroepiandrosterone.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call