7-nitroindazole-2-carboxamidine

7-Nitroindazole-2-carboxamidine is a synthetic small molecule belonging to the indazole class of organic compounds. It acts as an inhibitor of nitric oxide synthase, particularly endothelial nitric oxide synthase (NOS3). By binding at the substrate site of NOS, it disrupts normal enzyme function and inhibits the production of nitric oxide (NO), a key signaling molecule involved in vascular tone and neurotransmission. The compound has been studied structurally in complex with NOS enzymes and is considered experimental, with no approved medical indications or clinical trial activity reported. Its primary research interest lies in its potential neuroprotective effects via modulation of NO signaling pathways[1][3][5].

Other names

7-nitroindazole-2-carboxamidine7-nitroindazole-2-carboximidamide7-nitro-2h-indazole-2-carboximidamide6NP