8-demethyl-8-dimethylamino-flavin-adenine-dinucleotide

8-demethyl-8-dimethylamino-flavin-adenine-dinucleotide is a synthetic analog of flavin adenine dinucleotide (FAD), in which the flavin moiety is modified by replacing the methyl group at position 8 with a dimethylamino group. This compound belongs to the class of (3'→5') dinucleotides and has been studied primarily as an experimental molecule. It is structurally related to roseoflavin, an antibiotic riboflavin analog produced by Streptomyces davawensis, and its phosphorylated forms (such as RoFAD) act as antimetabolites that can interfere with flavoenzyme function. The primary mechanism involves acting as a cofactor analog for flavoenzymes, potentially inhibiting their normal activity due to altered redox properties or binding characteristics[1][7][8]. There are no approved therapeutic indications or clinical uses for this compound.