Drug intelligence / Profile preview

9-acetyl-2,3,4,9-tetrahydro-1H-carbazol-1-one

Development stage
Unknown
Modality
Small Molecules
01

Overview

MS7972 is a synthetic 1H-carbazol-1-one derivative that acts as a potent and selective inhibitor of cyclin-dependent kinase 5 (CDK5). It also functions as an antagonist of the P2Y1 receptor. It has been investigated as a lead compound for neurodegenerative diseases due to its CDK5 inhibitory activity.

Other names
9-Acetyl-2,3,4,9-tetrahydro-1H-carbazol-1-one9-acetyl-3,4-dihydro-2H-carbazol-1-oneCarbazole, tetrahydro-9-acetyl-
02

Targets

P2RY1 (Purinergic Receptor P2Y1)CDK5 (Cyclin-dependent kinase 5)

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