Drug intelligence / Profile preview

9-valent human papillomavirus vaccine + elasomeran

Development stage
Unknown
Lead developer
Merck
Modality
Recombinant Proteins and Enzymes, mRNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

9-valent human papillomavirus vaccine + elasomeran is a concomitant vaccination regimen consisting of the 9-valent recombinant human papillomavirus (HPV) vaccine (Gardasil 9) and the mRNA-1273 SARS-CoV-2 vaccine (elasomeran). Developed by Merck & Co. and Moderna, this regimen is being evaluated in Phase 3 clinical trials to assess the safety and immunogenicity of administering both vaccines together, particularly in children aged 9 to 11 years. The HPV component provides protection against HPV types 6, 11, 16, 18, 31, 33, 45, 52, and 58, which are associated with cervical cancer and other HPV-related diseases. The mRNA-1273 component is a nucleoside-modified messenger RNA vaccine that encodes the spike protein of the SARS-CoV-2 virus to prevent COVID-19. The study aims to facilitate healthcare delivery by reducing the number of visits required for adolescent immunization.

Brand names
Gardasil 9Gardasil9Gardasil-9Spikevax
Other names
9vHPV + mRNA-1273Gardasil 9 + Spikevax
02

Targets

SARS-CoV-2 spikeHPV L1 (Human papillomavirus L1 capsid protein)

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