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99mTc-Dar2

Development stage
Unknown
Modality
Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Nanobodies (VHH) → Antibody Fragments → Engineered Antibody Formats → Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

99mTc-Dar2 is a technetium-99m-labeled radiopharmaceutical, presumed to be a diagnostic agent used in nuclear medicine imaging. The "Dar" in the name suggests it may be a single-domain antibody (also known as nanobody) targeting a specific molecular marker, similar to other agents such as 99mTc-NM-02 which targets HER2 for breast cancer imaging[5][2]. Technetium-99m is widely used due to its favorable physical properties for SPECT imaging, including optimal gamma emission and short half-life[6]. However, no direct evidence or published data specifically describing the target or clinical use of "99mTc-Dar2" was found in the available sources. Based on naming conventions and analogs like 99mTc-NM-02, it is likely designed for noninvasive molecular imaging of tumors expressing a particular antigen.

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