99mTc-EC-G

99mTc-EC-G (technetium-99m-labeled ethylenedicysteine-glucosamine) is a SPECT radiopharmaceutical imaging agent developed by Cell>Point. It consists of ethylenedicysteine (EC) conjugated to glucosamine (G) molecules and labeled with the technetium-99m radioisotope. The agent is designed to target glucose metabolism by interacting with glucose transporters (GLUT) and hexokinase enzymes, which are typically overexpressed in malignant cells and ischemic tissues. 99mTc-EC-G is being developed as a more accessible and cost-effective alternative to 18F-FDG PET imaging for applications in oncology, specifically for the detection and staging of non-small cell lung cancer (NSCLC), and in cardiology for diagnosing myocardial ischemia in patients with coronary artery disease. It has also been investigated for the evaluation of rheumatic joint diseases.

Other names

technetium-99m-labeled ethylenedicysteine-glucosaminetechnetium99m-labeled ethylenedicysteine-glucosaminetechnetium 99m-labeled ethylenedicysteine-glucosamine99mTc-ethylenedicysteine-glucosamine99mTc-EC-glucosamine