Drug intelligence / Profile preview

99mtc-rwy

Development stage
Phase 1
Lead developer
Peking University
Modality
Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Peptides
Administration
Intravenous
01

Overview

99mTc-RWY is an experimental radiopharmaceutical composed of the RWY peptide labeled with the radionuclide technetium-99m. The RWY peptide targets integrin α6, a protein overexpressed in various tumors. By binding to integrin α6, 99mTc-RWY enables targeted imaging of tumors using single photon emission computed tomography (SPECT). Preclinical studies and early clinical imaging in breast cancer patients have demonstrated its ability to clearly visualize tumor lesions. This agent is under investigation primarily for cancer imaging applications, including colorectal and breast cancers[8].

Other names
technetium-99m rwytechnetium99m rwytechnetium 99m rwy99mTc-RWY
02

Targets

ITGA6 (Integrin alpha-6)

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