Drug intelligence / Profile preview

A-FERİN

Development stage
Unknown
Lead developer
Bilim Pharmaceuticals
Modality
Small Molecules
Administration
Oral
01

Overview

A-FERİN is a multi-ingredient combination pharmaceutical product developed and marketed by Bilim Pharmaceuticals, primarily indicated for the symptomatic relief of the common cold, influenza, and other upper respiratory tract infections. The standard formulation (typically provided as capsules) contains paracetamol, which acts as an analgesic and antipyretic to reduce pain and fever; chlorpheniramine maleate, a first-generation antihistamine that alleviates symptoms such as runny nose, sneezing, and watery eyes; and codeine phosphate, an opioid derivative that serves as an antitussive to suppress cough. Bilim Pharmaceuticals also offers several variants under the A-FERİN brand, including A-FERİN Forte (which lacks codeine), A-FERİN Sinus (which includes the decongestant pseudoephedrine), and pediatric formulations like A-FERİN Plus. It is a well-established marketed product in the Turkish pharmaceutical sector.

Brand names
A-FERİNA-FERİN ForteA-FERİN SinusA-FERİN PlusA-FERİN Hot
Other names
paracetamol + chlorpheniramine maleate + codeine phosphate
02

Targets

PGHS-1 (Prostaglandin G/H Synthase 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)HRH1 (Histamine H1 Receptor)MOR (Mu opioid receptor)

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