Drug intelligence / Profile preview

A006

Development stage
Phase 2
Modality
Small Molecules
Administration
Inhalation, Implant, Subcutaneous
01

Overview

"A006" is a code name that refers to several distinct entities within the provided context. One prominent entity is an Albuterol dry powder inhaler (DPI) formulation, developed for the treatment of asthma and bronchospasm. This formulation has undergone clinical studies to evaluate its efficacy, dose-ranging, and safety profiles. Another distinct entity is OIC-A006, an osteogenic inductive compound belonging to the amine family. OIC-A006 has been shown to promote osteogenesis both in vitro and in vivo by stimulating bone marrow mesenchymal stem cells and their expression of markers like alkaline phosphatase, osteopontin, osteocalcin, and core-binding factor a1, with potential applications in bone regeneration and healing of large segmental defects. Additionally, "A006" also refers to a Listeria bacteriophage, which is utilized for the rapid bioluminescence-based detection and differentiation of viable Listeria cells, integrating into bacterial tRNA genes.

Other names
Albuterol DPIListeria bacteriophage A006
02

Targets

ADRB2 (β2)

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