A1120

A1120 (also known as 2-[({4-[2-(trifluoromethyl)phenyl]piperidin‑1‑yl}carbonyl)amino]benzoic acid, CAS: 1152782‑19‑8), is a synthetic small molecule that functions as a potent and selective antagonist of the retinol binding protein 4 (RBP4). By inhibiting RBP4, it disrupts the transport of retinol (vitamin A alcohol), thereby reducing serum retinol levels. This mechanism has been investigated for potential therapeutic applications in metabolic diseases such as type II diabetes and related disorders. The compound is primarily used in research settings to study vitamin A metabolism and its role in metabolic disease[6][1].

Other names

2-[({4-[2-(trifluoromethyl)phenyl]piperidin‑1‑yl}carbonyl)amino]benzoic acid2-(4-(2-(Trifluoromethyl)phenyl)piperidine‑1-carboxamido)benzoic acid2‑(((4‑(2‑(trifluoromethyl)phenyl)piperidin‑1‑yl)carbonyl)amino)benzoic acid1152782–19–8