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A17
- Development stage
- Unknown
- Lead developer
- Bened Biomedical
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
A17 is a probiotic and psychobiotic strain of *Lactococcus lactis* developed by Bened Biomedical. Isolated from fermented cabbage in Taiwan, it is primarily utilized for allergy management and immune system modulation. The strain works by reducing serum immunoglobulin E (IgE) levels and balancing immune responses through the modulation of B-cells, T-cells, and the expression of pattern recognition receptors, specifically NOD-1, NOD-2, and TLR-4. A17 is effective in both its live and heat-killed (paraprobiotic) forms and is part of a portfolio of microbiome-based therapies targeting the gut-brain-immune axis.
- Other names
- Lactococcus lactis A17L. lactis A17
02
Targets
Acetylcholinesterase
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