Drug intelligence / Profile preview

A1DC + inactivated whole autologous HIV

Development stage
Preclinical
Lead developer
University of Pittsburgh
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular, Subcutaneous
01

Overview

An experimental HIV vaccine candidate that combines A1DC (likely an antibody or immunogen) with inactivated whole autologous HIV (patient's own inactivated HIV virus). This approach likely aims to induce broadly neutralizing antibodies against HIV as part of efforts to develop an effective preventive HIV vaccine.

Other names
autologous dendritic cell HIV vaccineSharon Riddler HIV vaccinea1DC + inactivated whole autologous HIVpgDC + inactivated whole autologous HIVa1DC + conserved HIV peptidespgDC + conserved HIV peptides
02

Targets

CD8A (CD8 alpha/beta Coreceptor)HIV (HIV-1 enzymes)

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