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A3 + vincristine
- Development stage
- Unknown
- Modality
- Small Molecules
- Administration
- Intravenous
01
Overview
A3 + vincristine is a combination therapy consisting of two agents. Vincristine is a well-established vinca alkaloid chemotherapy drug that inhibits microtubule formation, thereby blocking mitosis and arresting cell division in rapidly proliferating cancer cells[2][6][8]. It is used to treat various cancers, including leukemias, lymphomas, neuroblastoma, Wilms tumor, and rhabdomyosarcoma[2][6][8]. The identity of "A3" as a specific drug or compound could not be determined from the available data; it may refer to an investigational agent or code name for an experimental compound. As such, the mechanism of action and details for "A3" are unknown. This combination would be expected to have antineoplastic effects through at least the antimicrotubule activity of vincristine.
- Other names
- A3 + vincristine
02
Targets
TUBB (Tubulin (alpha and beta subunits))
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