Drug intelligence / Profile preview

A6

Development stage
Preclinical
Modality
Small Molecules, Live Biotherapeutic Products → Microbiome Therapeutics
Administration
Oral
01

Overview

"A6" is a non-specific identifier that refers to several distinct drug candidates. These include *Bifidobacterium animalis subsp. Lactis A6 Strain*, a probiotic being investigated for Irritable Bowel Syndrome - Diarrhoea (IBS-D) for its ability to improve symptoms. It also refers to a dihydropyridine-sulfonyl derivative compound, A6, which acts as an autophagy inducer and shows potential as an anticancer agent against various carcinoma cell lines (MCF-7, A549, SKOV-3, EA.yh926). Furthermore, "compound A6" is a small molecule that enhances TFAP2β condensation to suppress the development of esophageal squamous cell carcinoma.

Other names
Bifidobacterium animalis subsp. Lactis A6 Straindihydropyridine-sulfonyl derivative A6ESCC compound A6
02

Targets

TFAP2B (Transcription factor AP-2 beta)

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