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AAV-muscle
- Development stage
- Preclinical
- Lead developer
- Latus Bio
- Modality
- Gene Therapies
- Administration
- Intravenous
01
Overview
AAV-muscle is a preclinical gene therapy program being developed by Latus Bio, focusing on the treatment of genetic muscle disorders. The program utilizes Latus Bio's proprietary adeno-associated virus (AAV) capsid engineering platform to create vectors with enhanced tropism for skeletal and cardiac muscle tissues. By improving the specificity and potency of delivery, the AAV-muscle candidates aim to achieve therapeutic gene expression at lower systemic doses compared to conventional AAV serotypes like AAV9, potentially reducing the risk of liver toxicity and other dose-dependent adverse effects. The specific genetic targets and indications within the muscle disorder space have not yet been publicly disclosed, but the program leverages the company's broader expertise in refining AAV delivery to transform treatment for genetic diseases.
- Other names
- AAV-muscleLatus Bio muscle program
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