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AAV9-EGFP is a recombinant adeno-associated virus serotype 9 (AAV9) vector designed to deliver and express the enhanced green fluorescent protein (EGFP) reporter gene. In the context of gene therapy research, it is frequently employed as a control or reporter tool to evaluate the efficiency of viral transduction, tissue tropism, and promoter activity across various cell types and organs. AAV9 is particularly noted for its ability to cross the blood-brain barrier and transduce cells within the central nervous system, making AAV9-EGFP a valuable tool for studying neurodegenerative conditions like Canavan disease. The vector allows researchers to visualize and quantify gene delivery through the fluorescence of the EGFP protein.
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