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AB-2 is a peptide-based therapeutic candidate under development by Porosome Therapeutics for the treatment of melanoma. It belongs to the company's "Porosome Peptide Therapy" platform, which targets the porosome—a cup-shaped lipoprotein structure at the plasma membrane that serves as the universal secretory portal in cells. By modulating the secretory pathways through which cancer cells communicate or release growth factors, AB-2 aims to provide a novel approach to treating malignant melanoma. The drug is currently in the early-to-mid stages of development, following the company's lead melanoma candidate, AB-1.
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