Drug intelligence / Profile preview

AB-CD01

Development stage
Preclinical
Lead developer
University of Leicester
Modality
Live Biotherapeutic Products → Microbiome Therapeutics
01

Overview

**AB-CD01** is a preclinical, seven-bacteriophage cocktail developed for **Clostridioides difficile infection**. The product was licensed from the University of Leicester by AmpliPhi Biosciences as AmpliPhage-004 and was designed to use lytic bacteriophages to selectively infect and kill susceptible *C. difficile* bacteria. Public AmpliPhi materials described efficacy in an animal model and plans for manufacturing, but no clinical development of AB-CD01 was identified. ([sec.gov](https://www.sec.gov/Archives/edgar/data/921114/000114420416074960/v428747_ex99-1.htm))

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