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Abaxil is an anticoagulant medication developed and marketed by Saffron Pharma in Pakistan. It contains apixaban, a small molecule direct oral anticoagulant (DOAC). Apixaban acts as a selective, reversible, and direct inhibitor of Factor Xa, both free and clot-bound, as well as prothrombinase activity. By inhibiting Factor Xa, Abaxil prevents the conversion of prothrombin to thrombin, thereby inhibiting thrombus development. It is indicated for the prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation, the prevention of deep vein thrombosis (DVT) and pulmonary embolism (PE) following hip or knee replacement surgery, and the treatment and prevention of recurrence of DVT and PE.
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