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ABBV-291 is an investigational antineoplastic drug being developed by AbbVie for the treatment of relapsed or refractory non-Hodgkin lymphoma (NHL), including subtypes such as diffuse large B-cell lymphoma, follicular lymphoma, lymphoblastic lymphoma, mantle cell lymphoma, marginal zone lymphoma, and Waldenström macroglobulinemia. It is currently in Phase 1 clinical trials to determine its safety profile, pharmacokinetics, and efficacy in adults who have failed at least two prior lines of therapy. The precise mechanism of action has not been publicly defined as of the latest updates, but it is classified broadly as an antineoplastic agent. The drug is administered intravenously and trial participants are monitored for adverse events and changes in disease activity over a multi-year study period.
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