Drug intelligence / Profile preview

ABI-210

Development stage
Preclinical
Lead developer
Avirmax Biopharma
Modality
Gene Therapies
Administration
Intravitreal
01

Overview

ABI-210 is a preclinical-stage adeno-associated virus (AAV) gene therapy being developed by Avirmax Biopharma for the treatment of dry age-related macular degeneration (dAMD). The candidate utilizes Avirmax's proprietary AAV-S (synthetic) capsid technology, which is engineered to enhance gene delivery to the retina following intravitreal injection. The program aims to address the underlying pathology of dry AMD and geographic atrophy, though the specific therapeutic transgene has not been publicly disclosed. ABI-210 is designed to provide a long-term therapeutic effect through a single administration, potentially slowing or halting the progression of retinal degeneration.

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