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ABIO3419

Development stage: Unknown
Lead developer: Symatese
Modality: Implantable Hydrogels → Hydrogel Systems → Drug Delivery Systems, Non-biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Injectable Hydrogels → Hydrogel Systems → Drug Delivery Systems
Administration: Intraarticular

Overview

ABIO3419 is an intra-articular viscosupplementation gel developed by Abiogen Pharma for the treatment of knee osteoarthritis. The product consists of exogenous hyaluronic acid designed to replenish the diminished concentration and molecular weight of endogenous hyaluronan in the synovial fluid of osteoarthritic joints. By restoring the fluid's viscoelastic properties, ABIO3419 serves as a lubricant and shock absorber, thereby reducing joint pain and improving physical function. It has been evaluated in pivotal clinical trials to assess its safety and performance compared to standard treatments.

Other names: hyaluronic acid viscosupplementation gel

Targets

CD44 (CD44 antigen)

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