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Drug intelligence / Profile preview
Abiranamo
- Development stage
- Unknown
- Lead developer
- Shivnaam Tradelink
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
**Abiranamo** is a generic formulation of abiraterone acetate, an orally active, steroidal CYP17A1 inhibitor developed and marketed by Shivnaam Tradelink. It is indicated for the treatment of metastatic castration-resistant prostate cancer (mCRPC) and metastatic high-risk castration-sensitive prostate cancer (mCSPC), typically administered in combination with a corticosteroid such as prednisone or prednisolone. Abiranamo works by selectively and irreversibly inhibiting the cytochrome P450 17A1 (CYP17A1) enzyme, which catalyzes key steps in androgen biosynthesis within the testes, adrenal glands, and prostatic tumor tissues. This inhibition leads to a profound reduction in circulating testosterone levels, thereby slowing the progression of hormone-driven prostate cancer cells.
- Brand names
- Abiranamo
- Other names
- abiraterone acetate
02
Targets
CYP17A1 (Steroid 17-alpha-hydroxylase/C17,20 lyase)
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