Drug intelligence / Profile preview

ABL-101

Development stage
Unknown
Lead developer
Aurum Biosciences
Modality
Small Molecules, Nanoparticles → Drug Delivery Systems
Administration
Intravenous
01

Overview

ABL-101 is a novel perfluorocarbon (PFC)-based oxygen carrier and diagnostic imaging agent being developed by Aurum Biosciences. It functions as a therapeutic by delivering oxygen to ischemic or traumatized tissues; its particles are significantly smaller than red blood cells, enabling them to bypass vascular blockages or traverse collateral vessels. Additionally, it serves as a diagnostic tool through Glasgow Oxygen Level Dependent (GOLD) technology, which enhances MRI imaging to detect tissue under metabolic stress or inflammation. Originally known as Oxycyte, ABL-101 is administered intravenously in combination with supplemental oxygen and is being investigated for conditions including acute ischemic stroke, spinal cord injury, and various inflammatory diseases.

Other names
Oxycyte

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