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abobotulinumtoxinA + triamcinolone acetonide
- Development stage
- Preclinical
- Modality
- Small Molecules, Recombinant Proteins and Enzymes
- Administration
- Injection
01
Overview
A combination therapy consisting of abobotulinumtoxinA (Dysport), a botulinum toxin type A that blocks acetylcholine release, and triamcinolone acetonide, a corticosteroid with anti-inflammatory properties. This combination has demonstrated synergistic effects in treating pathologic scars and associated symptoms, particularly scar-related itching, with enhanced efficacy compared to triamcinolone alone.
- Brand names
- Dysport + Triamcinolone acetonide
- Other names
- Botulinum toxin type A + Triamcinolone acetonideBTA + TCA
02
Targets
GR (Glucocorticoid receptor)SNAP25 (Synaptosome-associated protein 25)NGF (Nerve growth factor)TRPV1 (Transient receptor potential cation channel subfamily V member 1)
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